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Acute Liver Injury and IgG4-related Autoimmune Pancreatitis following mRNA based COVID-19 vaccination

Ankoor Patel

2022Hepatology forum/Hepatology forum (Online)22 citationsDOIOpen Access PDF

Abstract

IgG4-related disease (IgG4-RD) is a fibro-inflammatory disease that can affect multiple organs. Autoimmune pancreatitis type 1 is a manifestation of IgG4-RD and can often mimic tumor-like masses. Autoimmune phenomena following COVID-19 mRNA vaccination are being increasingly reported. Currently, there are no cases in which IgG4-RD involving the hepatobiliary system has been reported following the COVID-19 vaccination. We present the first case of IgG4-RD and AIP type 1 to be associated with the mRNA-based COVID-19 vaccination.

Topics & Concepts

VaccinationAutoimmune pancreatitisMedicineCoronavirus disease 2019 (COVID-19)ImmunologyAutoimmune diseasePancreatitisDiseaseAntibodyGastroenterologyPathologyInfectious disease (medical specialty)IgG4-Related and Inflammatory DiseasesNeuroendocrine Tumor Research AdvancesPancreatitis Pathology and Treatment
Acute Liver Injury and IgG4-related Autoimmune Pancreatitis following mRNA based COVID-19 vaccination | Litcius