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G-protein activation by a metabotropic glutamate receptor

Alpay B. Seven, Ximena Barros-Álvarez, Marine de Lapeyrière, Makaía M. Papasergi-Scott, Michael J. Robertson, Chen‐Song Zhang, Robert M. Nwokonko, Yang Gao, Justin Meyerowitz, Jean‐Philippe Rocher, Dominik Schelshorn, Brian K. Kobilka, Jesper Mosolff Mathiesen, Georgios Skiniotis

2021Nature145 citationsDOIOpen Access PDF

Topics & Concepts

Heterotrimeric G proteinG protein-coupled receptorTransmembrane domainMetabotropic glutamate receptorMetabotropic receptorG proteinGq alpha subunitChemistryMetabotropic glutamate receptor 7Cell biologyBiophysicsTransmembrane proteinMetabotropic glutamate receptor 5BiochemistryGlutamate receptorReceptorBiologyReceptor Mechanisms and SignalingNeuroscience and Neuropharmacology ResearchProtein Kinase Regulation and GTPase Signaling
G-protein activation by a metabotropic glutamate receptor | Litcius