Enriched environment mitigates depressive behavior by changing the inflammatory activation phenotype of microglia in the hippocampus of depression model rats
Jingyang Gu, Yao‐Wei Xu, Lai-Peng Feng, Jiao Dong, Liqin Zhao, Cong Liu, Huiying Wang, Xiangyang Zhang, Cai Song, Changhong Wang
Topics & Concepts
MicrogliaHippocampal formationHippocampusInflammationProinflammatory cytokineMedicineBehavioural despair testInternal medicineEndocrinologyFluoxetineOpen fieldNeuroinflammationImmunologyAntidepressantReceptorSerotoninTryptophan and brain disordersNeuroinflammation and Neurodegeneration MechanismsStress Responses and Cortisol