Trends in Prevalence of Non-Valvular Atrial Fibrillation and Anticoagulation Therapy in a Japanese Region ― Analysis Using the National Health Insurance Database ―
Noritomo Narita, Ken Okumura, Takahiko Kinjo, Joko Mikami, Katsuko Tsushima, Reiko Takahashi, Makiko Noro, Ayaka Hashimoto, Teiko Sasaki, Misaki Takaki, Emiko Ishidoya, Yurika Narita, Hideno Imai, Emiko Ono, Hirofumi Tomita
Abstract
BACKGROUND: Direct oral anticoagulants (DOACs) are effective in reducing thromboembolism events in patients with non-valvular atrial fibrillation (NVAF). However, little is known about trends in NVAF prevalence and DOAC prescriptions in daily clinical practice. This study investigated the current status and trends in NVAF prevalence and DOAC prescriptions in a region of Japan. METHODS AND RESULTS: score ≥2 were not prescribed an OAC in 2017. CONCLUSIONS: By using the KDB we found that the prevalence of NVAF has increased gradually from 2014 to 2017. In the Tsugaru region in Japan, DOACs prescriptions increased and warfarin prescriptions decreased over the 4-year period.