Noncovalent molecular interactions between antineoplastic drug gemcitabine and a carrier protein identified through spectroscopic and in silico methods
Mohd Sajid Ali, Mohd Waseem, Naidu Subbarao, Hamad A. Al‐Lohedan
Topics & Concepts
GemcitabineQuenching (fluorescence)ChemistryLysozymeNon-covalent interactionsHydrophobic effectHydrogen bondIn silicoProtein secondary structureCrystallographyBiophysicsFluorescenceMoleculeBiochemistryOrganic chemistryCancerMedicinePhysicsInternal medicineBiologyQuantum mechanicsGeneProtein Interaction Studies and Fluorescence AnalysisDrug Transport and Resistance MechanismsProtein Structure and Dynamics