Rhodium<sup>III</sup>-catalyzed remote difunctionalization of arenes assisted by a relay directing group
Lincong Sun, Yuyao Zhao, Bingxian Liu, Junbiao Chang, Xingwei Li
Abstract
-olefins. The overall reaction represents C-C or N-C difunctionalization of the arene with the generation of diverse 2,3-dihydrobenzofuran platforms. The catalytic system proceeded with good efficiency, simple reaction conditions, and broad substrate scope. The diverse transformations of the products demonstrated the synthetic utility of this tandem reaction.
Topics & Concepts
RhodiumGroup (periodic table)CatalysisRelayChemistryCombinatorial chemistryMedicinal chemistryOrganic chemistryPhysicsQuantum mechanicsPower (physics)Catalytic C–H Functionalization MethodsCatalytic Cross-Coupling ReactionsAsymmetric Hydrogenation and Catalysis