An integrated network pharmacology approach reveals that Darutigenol reduces inflammation and cartilage degradation in a mouse collagen-induced arthritis model by inhibiting the JAK-STAT3 pathway
Yong Wang, Hui Yan, Long Zhao, Xuelai He, Te‐Ri‐Gen Bao, Xian-Duo Sun, Yong-Cheng Yang, Shu-Yi Zhu, Xiaoxu Gao, An‐Hua Wang, Jing‐Ming Jia, Jing‐Ming Jia
Topics & Concepts
InflammationArthritisCollagen-induced arthritisCartilageMedicineSTAT3Signal transductionPharmacologyBiologyImmunologyCell biologyAnatomyRheumatoid Arthritis Research and TherapiesSpondyloarthritis Studies and TreatmentsOsteoarthritis Treatment and Mechanisms