Transient Mitochondria Dysfunction Confers Fungal Cross-Resistance against Phagocytic Killing and Fluconazole
Sofía Siscar-Lewin, Toni Gabaldón, Alexander Maximilian Aldejohann, Oliver Kurzai, Bernhard Hube, Sascha Brunke
Abstract
Candida glabrata is an opportunistic pathogen whose incidence has been increasing in the last 40 years. It has risen to become the most prominent non- Candida albicans Candida (NCAC) species to cause candidemia, constituting about one-third of isolates in the United States, and steadily increasing in European countries and in Australia.
Topics & Concepts
FluconazoleCandida albicansMicrobiologyCandida glabrataIncidence (geometry)PathogenFungal pathogenDrug resistanceBiologyAntifungalMedicineImmunologyPhysicsOpticsAntifungal resistance and susceptibilityFungal Infections and StudiesPlant Pathogens and Fungal Diseases