Revealing PACMA 31 as a new chemical type TrxR inhibitor to promote cancer cell apoptosis
Qianhe Xu, Junmin Zhang, Zhengjia Zhao, Yajun Chu, Jianguo Fang
Topics & Concepts
Thioredoxin reductaseThioredoxinCancer cellReactive oxygen speciesChemistryBiochemistryGlutathioneCell biologySelenocysteineApoptosisOxidative stressCancerBiologyEnzymeCysteineGeneticsRedox biology and oxidative stressGlutathione Transferases and PolymorphismsFree Radicals and Antioxidants