Tumor immune evasion through loss of MHC class-I antigen presentation
Gülce Sarı, Kenneth L. Rock
Topics & Concepts
MHC class IAntigen presentationCD8AntigenMajor histocompatibility complexImmunologyAntigen processingImmune systemCytotoxic T cellEvasion (ethics)BiologyImmune checkpointBlockadeMHC restrictionCross-presentationImmunotherapyT cellCancer researchReceptorGeneticsIn vitroImmunotherapy and Immune ResponsesCAR-T cell therapy researchImmune Cell Function and Interaction