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Vascular alterations among young adults with SARS-CoV-2

Stephen M. Ratchford, Jonathon L. Stickford, Valesha M. Province, Nina L. Stute, Marc A. Augenreich, Laurel K. Koontz, Landry K. Bobo, Abigail S. L. Stickford

2020American Journal of Physiology-Heart and Circulatory Physiology181 citationsDOIOpen Access PDF

Abstract

This study was the first to investigate the vascular implications of contracting SARS-CoV-2 among young, otherwise healthy adults. Using a cross-sectional design, this study assessed vascular function 3-4 wk after young adults tested positive for SARS-CoV-2. The main findings from this study were a strikingly lower vascular function and a higher arterial stiffness compared with healthy controls. Together, these results suggest rampant vascular effects seen weeks after contracting SARS-CoV-2 in young adults.

Topics & Concepts

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Coronavirus disease 2019 (COVID-19)VirologyMedicine2019-20 coronavirus outbreakInternal medicineOutbreakInfectious disease (medical specialty)DiseaseLong-Term Effects of COVID-19COVID-19 Clinical Research StudiesPeripheral Artery Disease Management
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