Loss of vacuolar acidity results in iron-sulfur cluster defects and divergent homeostatic responses during aging in Saccharomyces cerevisiae
Kenneth L. Chen, Toby N. Ven, Matthew M. Crane, Matthew L. C. Brunner, Adrian K. Pun, Kathleen L. Helget, Katherine Brower, Dexter E. Chen, Ha Doan, Justin D. Dillard-Telm, Ellen Huynh, Yen-Chi Feng, Zili Yan, Alexandra Golubeva, Roy A. Hsu, Raheem Knight, Jessie Levin, Vesal Mobasher, Michael Muir, Victor Omokehinde, Corey Screws, Esin Tunali, Rachael K. Tran, Luz Valdez, Edward Yang, Scott R. Kennedy, Alan J. Herr, Matt Kaeberlein, Brian M. Wasko
Topics & Concepts
RegulonIron–sulfur clusterSaccharomyces cerevisiaeBiologyMutantPhenotypeCell biologyHomeostasisGeneticsIron deficiencyYeastBiochemistryGeneInternal medicineMedicineEnzymeAnemiaFungal and yeast genetics researchEndoplasmic Reticulum Stress and DiseaseGenetics, Aging, and Longevity in Model Organisms