Sustained treatment with an α5 GABA A receptor negative allosteric modulator delays excitatory circuit development while maintaining GABAergic neurotransmission
Jessica L. Nuwer, Megan L. Brady, Nadya Povysheva, Amanda Coyne, Tija C. Jacob
Topics & Concepts
Excitatory postsynaptic potentialNeuroscienceGephyrinInhibitory postsynaptic potentialExcitatory synapseNeurotransmissionAMPA receptorNMDA receptorSynaptic plasticityLong-term potentiationDendritic spineGABAergicGABAA receptorBiologyHippocampal formationReceptorGlycine receptorGlycineBiochemistryAmino acidNeuroscience and Neuropharmacology ResearchNeural dynamics and brain functionMemory and Neural Mechanisms