Multifunctional pathology-mapping theranostic nanoplatforms for US/MR imaging and ultrasound therapy of atherosclerosis
Binyang Gao, Jinshun Xu, Jie Zhou, Huan Zhang, Rui Yang, Hong Wang, Jianbo Huang, Feng Yan, Yan Luo
Abstract
-weighted signal. The apoptosis of macrophages and disaggregation of activated platelets on the plaques were also confirmed in vivo. In summary, this study provides a potential strategy for a tailored treatment of vulnerable plaques based on their pathological nature and a multimodal imaging tool for the risk stratification and assessment of therapeutic efficacy.
Topics & Concepts
SchematicPathologicalMedicinePathologyEngineeringElectronic engineeringUltrasound and Hyperthermia ApplicationsPhotoacoustic and Ultrasonic ImagingNanoparticle-Based Drug Delivery