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HIV-1 gp120-Induced Endolysosome de-Acidification Leads to Efflux of Endolysosome Iron, and Increases in Mitochondrial Iron and Reactive Oxygen Species

Peter W. Halcrow, Koffi L. Lakpa, Nabab Khan, Zahra Afghah, Nicole Miller, Gaurav Datta, Xuesong Chen, Jonathan D. Geiger

2021Journal of Neuroimmune Pharmacology40 citationsDOIOpen Access PDF

Topics & Concepts

DeferoxamineReactive oxygen speciesOxidative stressMitochondrionMitochondrial ROSChemistryCytosolFerrousCell biologyPharmacologyBiologyBiochemistryEnzymeOrganic chemistryHIV Research and TreatmentCalcium signaling and nucleotide metabolismMosquito-borne diseases and control
HIV-1 gp120-Induced Endolysosome de-Acidification Leads to Efflux of Endolysosome Iron, and Increases in Mitochondrial Iron and Reactive Oxygen Species | Litcius