Urolithin A-induced mitophagy suppresses apoptosis and attenuates intervertebral disc degeneration via the AMPK signaling pathway
Jialiang Lin, Jinru Zhuge, Xuan-Qi Zheng, Yuhao Wu, Zengjie Zhang, Tianzhen Xu, Zaher Meftah, Hongming Xu, Yaosen Wu, Naifeng Tian, Weiyang Gao, Yifei Zhou, Xiaolei Zhang, Xiangyang Wang
Topics & Concepts
AMPKMitophagyDegeneration (medical)ApoptosisIntervertebral discCell biologySignal transductionNeuronal degenerationChemistryMedicineAutophagyBiologyAnatomyPhosphorylationPathologyProtein kinase ABiochemistryDiseasePomegranate: compositions and health benefitsParaoxonase enzyme and polymorphismsPlant-derived Lignans Synthesis and Bioactivity