Targeting drug delivery and efficient lysosomal escape for chemo-photodynamic cancer therapy by a peptide/DNA nanocomplex
Qiusheng Wang, Ziyun He, Hai Zhu, Wenxia Gao, Nan Zhang, Jing Li, Jianqin Yan, Bin He, Xueting Ye
Abstract
Our study demonstrated a biocompatible peptide/DNA composite nanoplatform for combinational cancer therapy via the targeted delivery of therapeutic agents and efficient lysosomal escape.
Topics & Concepts
Photodynamic therapyPeptideDrugDrug deliveryCancerCancer researchDNACancer therapyAnticancer drugTargeted drug deliveryNanotechnologyPharmacologyMaterials scienceMedicineChemistryBiochemistryInternal medicineOrganic chemistryAdvanced biosensing and bioanalysis techniquesRNA Interference and Gene DeliveryNanoplatforms for cancer theranostics