Bone marrow and periosteal skeletal stem/progenitor cells make distinct contributions to bone maintenance and repair
Elise Jeffery, Terry L.A. Mann, Jade A. Pool, Zhiyu Zhao, Sean J. Morrison
Abstract
bone marrow stromal cells that expressed hematopoietic niche factors at fracture sites. Different bone injuries are thus repaired by different SSCs, with periosteal cells regenerating bone and marrow stroma after non-stabilized fractures.
Topics & Concepts
PeriosteumBone marrowProgenitor cellBiologyBone healingStem cellStromal cellBone cellCell biologyAnatomyImmunologyCancer researchMesenchymal stem cell researchHematopoietic Stem Cell TransplantationBone and Joint Diseases