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Ergolide covalently binds NLRP3 and inhibits NLRP3 inflammasome-mediated pyroptosis

Miao Ren, Jiahao Chen, Haowen Xu, Weifeng Li, Tingting Wang, Zhanghuan Chi, Yi Lin, Anqi Zhang, Gaozhi Chen, Xu Wang, Xiaoyu Sun, Guang Liang, Junlu Wang, Wu Luo, Junlu Wang, Wu Luo

2023International Immunopharmacology16 citationsDOI

Topics & Concepts

PyroptosisInflammasomePyrin domainErgLipopolysaccharidePharmacologyChemistryMedicineImmunologyInflammationBiochemistryRetinalInflammasome and immune disordersInflammation biomarkers and pathwaysImmune Response and Inflammation
Ergolide covalently binds NLRP3 and inhibits NLRP3 inflammasome-mediated pyroptosis | Litcius