Overexpression of POU3F2 promotes radioresistance in triple-negative breast cancer via Akt pathway activation
Han Zhang, Jieling Zheng, Yiming Fu, Ling Jing, ZiShen Liu, Xiaotong Lin, Xin Dong, Yao Sun, Tingting Tan, Zhaoze Guo, Guozhu Xie
Topics & Concepts
RadioresistanceTriple-negative breast cancerBreast cancerCancer researchClonogenic assayProtein kinase BCancerGene knockdownRadiosensitivityPI3K/AKT/mTOR pathwayCancer cellMTT assayBiologyCell growthMedicineIn vivoInternal medicineSignal transductionRadiation therapyCell cultureCell biologyGeneticsBiotechnologyBiomarkers in Disease MechanismsAxon Guidance and Neuronal SignalingCancer-related gene regulation