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Polystyrene nanoplastics induce lipophagy via the AMPK/ULK1 pathway and block lipophagic flux leading to lipid accumulation in hepatocytes

Zhuying Fan, Yukang Zhang, Yuting Fang, Huiyuan Zhong, Tingting Wei, Huraira Akhtar, Jiahuai Zhang, Man Yang, Yanbo Li, Xianqing Zhou, Zhiwei Sun, Ji Wang

2024Journal of Hazardous Materials44 citationsDOI

Topics & Concepts

AMPKULK1Cell biologyChemistryPolystyreneFlux (metallurgy)KinaseBiologyProtein kinase APolymerOrganic chemistryMicroplastics and Plastic Pollutionbiodegradable polymer synthesis and propertiesGraphene and Nanomaterials Applications
Polystyrene nanoplastics induce lipophagy via the AMPK/ULK1 pathway and block lipophagic flux leading to lipid accumulation in hepatocytes | Litcius