68Ga-PSMA Uptake Patterns of Clear Cell Renal Carcinoma Across Different Histopathological Subtypes
Melis Oflas, Yasemin Ozluk, Oner Sanli, Zeynep Gozde Ozkan, Serkan Kuyumcu
Abstract
ABSTRACT: 68Ga-prostate-specific membrane antigen (PSMA) PET/CT is a well-established imaging modality in patients with prostate cancer; however, PSMA expression is also reported in the tumor-associated neovasculature, including but not limited to hepatocellular carcinoma, breast cancer, and renal cell carcinoma. Herein, we present 2 patients diagnosed with different histopathological subtypes of renal cell carcinoma who underwent 68Ga-PSMA PET/CT before surgery. Both cases have different PSMA expression characteristics and are presented along with pathological findings.
Topics & Concepts
MedicinePathologyPathologicalClear cell renal cell carcinomaClear cellRenal cell carcinomaHepatocellular carcinomaKidneyClear cell carcinomaCellImmunohistochemistryProstate carcinomaCarcinomaProstatePapillary renal cell carcinomasKidney diseaseOncologyHistopathological examinationAntigenProstate Cancer Treatment and ResearchRadiopharmaceutical Chemistry and ApplicationsProstate Cancer Diagnosis and Treatment