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Hydantoin based dual inhibitors of ALR2 and PARP-1: Design, synthesis, in-vitro and in-vivo evaluation

Manoj Kumar, Pankaj Kumar Singh, Shalki Choudhary, Om Silakari

2022Bioorganic Chemistry13 citationsDOI

Topics & Concepts

Aldose reductaseChemistryIn silicoIn vivoPoly ADP ribose polymeraseIn vitroBiochemistryAldehyde ReductasePharmacologyPolyol pathwayEnzymePolymeraseBiologyGeneBiotechnologyAldose Reductase and TaurineEnzyme function and inhibitionFree Radicals and Antioxidants
Hydantoin based dual inhibitors of ALR2 and PARP-1: Design, synthesis, in-vitro and in-vivo evaluation | Litcius