Tumor Microenvironment-triggered Nanosystems as dual-relief Tumor Hypoxia Immunomodulators for enhanced Phototherapy
Zijun Shen, Junfei Xia, Qingming Ma, Wei Zhu, Zhen Gao, Shangcong Han, Yan Liang, Jie Cao, Yong Sun
Abstract
The proposed novel nanosystems represent an important advance in altering TME for improved clinical PDT efficacy, as well as their potential as effective theranostic agents in cancer treatment.
Topics & Concepts
Photodynamic therapyTumor microenvironmentPhotothermal therapyIndocyanine greenTumor hypoxiaReactive oxygen speciesCancer researchChemistryCancer cellIn vivoHypoxia (environmental)CancerRadiation therapyNanotechnologyMaterials scienceOxygenMedicineTumor cellsPathologyBiochemistryInternal medicineOrganic chemistryBiotechnologyBiologyNanoplatforms for cancer theranosticsPhotodynamic Therapy Research StudiesLuminescence and Fluorescent Materials