Reactivation of dysfunctional dendritic cells by a stress-relieving nanosystem resets anti-tumor immune landscape
Yichao Lu, Yingying Shi, Zhenyu Luo, Xuemeng Guo, Mengshi Jiang, Xiang Li, Junlei Zhang, Chunqi Zhu, Hang Yin, Bing Qin, Xu Liu, Jiaxin Huang, Yongzhong Du, Lihua Luo, Jian You
Topics & Concepts
XBP1Immune systemUnfolded protein responseTumor microenvironmentCancer researchAdoptive cell transferDendritic cellCell biologyNADPH oxidaseEndoplasmic reticulumImmunologyChemistryReactive oxygen speciesBiologyT cellBiochemistryRNA splicingRNAGeneImmunotherapy and Immune ResponsesCancer Immunotherapy and BiomarkersNanoplatforms for cancer theranostics