Effects of fentanyl overdose-induced muscle rigidity and dexmedetomidine on respiratory mechanics and pulmonary gas exchange in sedated rats
Philippe Haouzi, Nicole Tubbs
Abstract
The decrease in respiratory compliance and increased metabolism-induced hypoxemia produced by an overdose of fentanyl, in and of themselves, contribute to fentanyl toxicity.
Topics & Concepts
FentanylAnesthesiaDexmedetomidineMedicineRespiratory systemRespiratory rateMuscle RigidityHeart rateSedationInternal medicineBlood pressurePain Mechanisms and TreatmentsVeterinary Pharmacology and AnesthesiaAnesthesia and Sedative Agents