Rational design and eco-friendly one-pot multicomponent synthesis of novel ethylidenehydrazineylthiazol-4(5H)-ones as potential apoptotic inducers targeting wild and mutant EGFR-TK in triple negative breast cancer
Eslam M. Abbass, Ahmed A. Al‐Karmalawy, Marwa Sharaky, Muhammad Khattab, Abdullah Yahya Abdullah Alzahrani, Aya I. Hassaballah
Topics & Concepts
T790MChemistryEGFR inhibitorsApoptosisEpidermal growth factor receptorCancer researchMutantCancer cellPharmacologyCancerBiochemistryReceptorBiologyGeneticsGeneGefitinibSynthesis and biological activityCancer therapeutics and mechanismsSynthesis and Characterization of Heterocyclic Compounds