<i>In silico</i> analysis of energy interactions between nociceptin/orfanin FQ receptor and two antagonists with potential antidepressive action
John Lenon de Souza Santos, Katyanna Sales Bezerra, Emmanuel Duarte Barbosa, Anne Pereira, Ywlliane da Silva Rodrigues Meurer, Jonas Ivan Nobre Oliveira, Elaine C. Gavioli, Umberto L. Fulco
Abstract
This study addresses the binding energies of NOPR-ligand complexes and presents the main amino acid residues involved in the interaction between these complexes.
Topics & Concepts
ChemistryNociceptin receptorIn silicoAction (physics)PharmacologyReceptorStereochemistryBiochemistryOpioidMedicinePhysicsQuantum mechanicsGeneOpioid peptideNeuropeptides and Animal PhysiologyReceptor Mechanisms and SignalingCardiovascular, Neuropeptides, and Oxidative Stress Research