Biomarkers for assessment of intestinal permeability in clinical practice
Benjamin Seethaler, Maryam Basrai, Audrey M. Neyrinck, Julie‐Anne Nazare, Jens Walter, Nathalie M. Delzenne, Stephan C. Bischoff
2021American Journal of Physiology-Gastrointestinal and Liver Physiology230 citationsDOIOpen Access PDF
Abstract
This study shows that biomarkers from blood and fecal samples are associated with the cumbersome established tests of intestinal permeability throughout different cohorts. Therefore, such biomarkers could be used to assess gut barrier function in prospective cohort studies and large-scale clinical trials for which tracer-based tests may not be feasible.
Topics & Concepts
Intestinal permeabilityMedicineProspective cohort studyClinical PracticeCohortClinical trialInternal medicinePhysical therapyGut microbiota and healthIron Metabolism and DisordersDrug Transport and Resistance Mechanisms