SARS-CoV-2 Reinfection in a Liver Transplant Recipient
Christopher H. Tomkins-Tinch, Jennifer S. Daly, Adrianne Gladden-Young, Nicole Theodoropoulos, Michael P. Madaio, Neng Yu, Vijay K. Vanguri, Katherine J. Siddle, Gordon Adams, Lydia A. Krasilnikova, Babak Movahedi, Adel Bozorgzadeh, Karl Simin, Jacob E. Lemieux, Jeremy Luban, Daniel J. Park, Bronwyn MacInnis, Pardis C. Sabeti, Stuart M. Levitz
Abstract
We present a case of a liver transplant recipient with 2 distinct SARS-CoV-2 infections, separated by 111 days without symptoms and 2 negative test results for SARS-CoV-2 infection. The clinical course suggested reinfection, and viral genomic sequencing was used to distinguish whether the later positive samples were due to SARS-CoV-2 relapse or reinfection.
Topics & Concepts
MedicineLiver transplantationSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)VirologyImmunologyCoronavirus disease 2019 (COVID-19)Internal medicineTransplantationDiseaseInfectious disease (medical specialty)SARS-CoV-2 and COVID-19 ResearchSARS-CoV-2 detection and testingCOVID-19 Clinical Research Studies