Modular Approach to the Functionalization of Polymersomes
Sjoerd J. Rijpkema, Sabine G. H. A. Langens, Marnix R. van der Kolk, Katerina Gavriel, B. Jelle Toebes, Daniela A. Wilson
Abstract
-PDLLA with various functional groups derived from the amine-functionalized polymers, leading to functionally active polymersomes. We show that polymersome formation is possible via the general method with all functionalized groups and that these handles are present on the surface and are able to undergo reactions. Additionally, this methodology provides a general synthetic tool to tailor the functional group of the polymersome right before self-assembly, without limitation on the reaction conditions.
Topics & Concepts
PolymersomeSurface modificationCombinatorial chemistryChemistryPEG ratioNanotechnologyAmine gas treatingPolymerMaterials scienceOrganic chemistryCopolymerAmphiphileEconomicsPhysical chemistryFinanceChemical Synthesis and AnalysisAdvanced Polymer Synthesis and CharacterizationInnovative Microfluidic and Catalytic Techniques Innovation