UJI AKTIVITAS ANTIINFLAMASI EKSTRAK ETANOL DAUN KAYU MANIS (Cinnamomum burmanni) PADA MENCIT PUTIH JANTAN
Rahmila Yuni Astika, Fathnur Sani K, Elisma Elisma
Abstract
Cinnamon (Cinnamomum burmannii) leaves extract contains secondary metabolites such as flavonoids, saponins, tannins, alakloids, steroids/terpenoids and phenols. The aims of this study was to examine the anti-inflammatory activity of the ethanolic extract of cinnamon leaves topically and to determine the best concentration for the treatment of inflammation. This research is an experimental research with a post test only control group design approach. The treatment group was devided into 5 groups where each treatment consisted of 7 test animals The treatments included positive control (hydrocortisone acetate 2.5%), negative control (vaselin flavum), ethanol extract of cinnamon leaves with concentrations of 5%, 10% and 20%. The results showed that the ethanolic extract of cinnamon leaves had an anti-inflammatory effect statistically had a significant difference between the treatment groups (p<0.05). The best concentration is 20% then followed by 10% and 5%.