Electronic control over site-selectivity in hydrogen atom transfer (HAT) based C(sp<sup>3</sup>)–H functionalization promoted by electrophilic reagents
Marco Galeotti, Michela Salamone, Massimo Bietti
Abstract
)-H bond functionalization site-selectivity. Through an analysis of the recent literature, a detailed description of the HAT reagents employed in these processes, the associated mechanistic features and the selectivity patterns observed in the functionalization of substrates of increasing structural complexity will be provided.
Topics & Concepts
ReagentElectrophileSelectivitySurface modificationChemistrySubstrate (aquarium)Hydrogen atomCombinatorial chemistryAtom (system on chip)PhotochemistryOrganic chemistryCatalysisPhysical chemistryGroup (periodic table)Computer scienceEmbedded systemGeologyOceanographyCatalytic C–H Functionalization MethodsSynthesis and Catalytic ReactionsRadical Photochemical Reactions