Tumor microenvironment-activatable Fe-doxorubicin preloaded amorphous CaCO <sub>3</sub> nanoformulation triggers ferroptosis in target tumor cells
Chencheng Xue, Menghuan Li, Yang Zhao, Jun Zhou, Yan Hu, Kaiyong Cai, Yanli Zhao, Shu‐Hong Yu, Zhong Luo
Abstract
This study describes a ferroptosis/apoptosis-based treatment strategy via the cooperation between Fe 2+ and doxorubicin.
Topics & Concepts
DoxorubicinCancer researchChemistryCellMedicineChemotherapyBiochemistryInternal medicineFerroptosis and cancer prognosisExtracellular vesicles in diseaseNanoplatforms for cancer theranostics