The Burden of Overweight and Obesity-Associated Gastrointestinal Cancers in Low and Lower-Middle-Income Countries: A Global Burden of Disease 2019 Analysis
Pojsakorn Danpanichkul, Thanida Auttapracha, Banthoon Sukphutanan, Cheng Han Ng, Phuuwadith Wattanachayakul, Siwanart Kongarin, Priyata Dutta, Kwanjit Duangsonk, Jerapas Thongpiya, Mark Muthiah, Daniel Q. Huang, Rashid N. Lui, Yuya Seko, Kazuhiro Takahashi, Mazen Noureddin, Ju Dong Yang, Michael B. Wallace, Karn Wijarnpreecha
Abstract
INTRODUCTION: Obesity is associated with cancer, including gastrointestinal (GI). Data from low (LICs) and lower-middle-income countries (MICs) are limited. METHODS: We utilized data from the Global Burden of Disease Study 2019 to determine the mortality from GI cancer risk of high body mass index (BMI) in these countries. RESULTS: Mortality rates of GI cancers from high BMI increased in LICs and lower MICs, while burdens decreased or remained stable in high and middle-income countries. DISCUSSION: The GI cancer-related burden from high BMI increased in LICs and lower MICs, necessitating a concerted effort to tackle the obesity pandemic.