CRISPR screening and cell line IC50 data reveal novel key genes for trametinib resistance
Hengrui Liu, Panpan Wang
Topics & Concepts
CRISPRTrametinibGeneHematologyMega-Key (lock)Line (geometry)BiologyComputational biologyGeneticsImmunologyAstronomyGeometryPhysicsEcologyMAPK/ERK pathwayMathematicsKinaseProtein Degradation and InhibitorsCancer Genomics and DiagnosticsHIV/AIDS drug development and treatment