Litcius/Paper detail

Gefitinib vs Gefitinib Plus Pemetrexed and Carboplatin Chemotherapy in <i>EGFR</i>-Variant Lung Cancer—Long-Term Results of a Randomized Clinical Trial

Vanita Noronha, Vijay Patil, Nandini Menon, Minit Shah, Anuradha Chougule, Zoya Peelay, Kumar Prabhash

2024JAMA Oncology12 citationsDOIOpen Access PDF

Abstract

This randomized clinical trial examines whether adding chemotherapy with pemetrexed and carboplatin to gefitinib improves survival among patients with epidermal growth factor receptor ( EGFR )–variant non–small cell lung cancer.

Topics & Concepts

GefitinibPemetrexedMedicineCarboplatinLung cancerOncologyInternal medicineEpidermal growth factor receptorChemotherapyRandomized controlled trialClinical trialCancerCisplatinLung Cancer Treatments and MutationsLung Cancer Diagnosis and TreatmentGastric Cancer Management and Outcomes