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Perfluorooctane sulfonate interferes with non-genomic estrogen receptor signaling pathway, inhibits ERK1/2 activation and induces apoptosis in mouse spermatocyte-derived cells

Jianhua Qu, Yu Han, Ziyan Zhao, Yuan Wu, Ying Lü, Gang Chen, Junkang Jiang, Lianglin Qiu, Aihua Gu, Xinru Wang

2021Toxicology25 citationsDOI

Topics & Concepts

SpermatocyteEstrogen receptorApoptosisAgonistChemistrySignal transductionReceptorCell biologyPerfluorooctaneXenoestrogenBiologyMolecular biologyBiochemistryGeneSodiumGeneticsBreast cancerSulfonateOrganic chemistryCancerMeiosisPer- and polyfluoroalkyl substances researchEffects and risks of endocrine disrupting chemicalsEstrogen and related hormone effects
Perfluorooctane sulfonate interferes with non-genomic estrogen receptor signaling pathway, inhibits ERK1/2 activation and induces apoptosis in mouse spermatocyte-derived cells | Litcius