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Design, synthesis and biological evaluation of novel diosgenin–benzoic acid mustard hybrids with potential anti-proliferative activities in human hepatoma HepG2 cells

Jinling Zhang, Wenbao Wang, Yanzhao Tian, Liwei Ma, Lin Zhou, Hao Sun, Yukun Ma, Huiling Hou, Xiaoli Wang, Jin Ye, Xiaobo Wang

2022Journal of Enzyme Inhibition and Medicinal Chemistry10 citationsDOIOpen Access PDF

Abstract

serves as a promising anti-hepatoma lead compound that deserves further research.

Topics & Concepts

DiosgeninBenzoic acidChemistryHybridBiochemistryCombinatorial chemistryPharmacologyStereochemistryCancer researchBiologyOrganic chemistryBotanyPhytochemical Studies and BioactivitiesNatural product bioactivities and synthesisPhytochemistry and Biological Activities
Design, synthesis and biological evaluation of novel diosgenin–benzoic acid mustard hybrids with potential anti-proliferative activities in human hepatoma HepG2 cells | Litcius