Cell membrane fusion induced by surface modification with cell-penetrating peptide–lipid conjugates that facilitates close contact between distinct membranes
Yuya Sato, Teruhiko Baba, Takeyuki Uchida, Ung-il Chung, Yuji Teramura
Abstract
Tat peptide-conjugated PEG-lipids (Tat-PEG-lipid) are spontaneously incorporated into the bilayer membrane and facilitate the fusion between liposomes.
Topics & Concepts
Lipid bilayer fusionMembraneLiposomeLipid bilayerPeptideCellCell membraneChemistryConjugateBiophysicsConjugated systemPEG ratioCell biologyBiochemistryBiologyOrganic chemistryPolymerFinanceMathematicsEconomicsMathematical analysisRNA Interference and Gene DeliveryAdvanced biosensing and bioanalysis techniquesLipid Membrane Structure and Behavior