Salidroside attenuates myocardial remodeling in DOCA-salt-induced mice by inhibiting the endothelin 1 and PI3K/AKT/NFκB signaling pathways
Qiao Liu, Qingman Luo, Bin Zhong, Kecheng Tang, Xueling Chen, Shengqian Yang, Xiaohui Li
Topics & Concepts
SalidrosidePI3K/AKT/mTOR pathwayMyocardial fibrosisMedicineProtein kinase BVentricular remodelingFibrosisPharmacologyEndothelin 1StimulationSignal transductionInflammationCardioprotectionNF-κBInternal medicineHeart failureEndocrinologyChemistryBiochemistryMyocardial infarctionReceptorMedicinal Plants and Bioactive CompoundsHormonal Regulation and HypertensionParaoxonase enzyme and polymorphisms