Semisynthetic pleuromutilin antimicrobials with therapeutic potential against methicillin-resistant Staphylococcus aureus by targeting 50S ribosomal subunit
Xiao Wang, Rui Wang, Zhaosheng Zhang, Guang‐Yu Zhang, Zhen Jin, Rong Shen, Dan Du, You‐Zhi Tang
Topics & Concepts
Staphylococcus aureusIn vivoChemistryMicrobiologyIn vitroAntimicrobialMinimum inhibitory concentrationMethicillin-resistant Staphylococcus aureusMinimum bactericidal concentrationPharmacokineticsAntibacterial activityPharmacologyBacteriaBiologyBiochemistryGeneticsBiotechnologyVeterinary medicine and infectious diseasesSynthesis and Biological EvaluationToxin Mechanisms and Immunotoxins