A systematic review and meta-analysis of intraday effects of ambient air pollution and temperature on cardiorespiratory morbidities: First few hours of exposure matters to life
Keyu Wu, Hung Chak Ho, Hong Su, Cunrui Huang, Hao Zheng, Wenyi Zhang, Junwen Tao, Mohammad Zahid Hossain, Yunquan Zhang, Kejia Hu, Min Yang, Qiyue Wu, Zhiwei Xu, Jian Cheng
Abstract
BACKGROUND: A growing number of studies have reported an increased risk of cardiovascular disease (CVD) and respiratory disease (RD) within hours after exposure to ambient air pollution or temperature. We assemble published evidence on the sub-daily associations of CVD and RD with ambient air pollution and temperature. METHODS: in particulate matters, 0.1 ppm in CO, and 10 ppb in other gaseous pollutants. FINDINGS: , and an increased risk of out-of-hospital cardiac arrest morbidity within 12 h after exposure to CO. Risk of total CVD also increased within 24 h after exposure to heat. INTERPRETATION: This study supports a sudden risk increase of cardiorespiratory diseases within a few hours after exposure to air pollution or heat, and some acute and highly lethal diseases such as myocardial infarction and cardiac arrest could be affected within a shorter time. FUNDING: The National Natural Science Foundation of China (Grant No. 42105165; 81773518), the High-level Scientific Research Foundation of Anhui Medical University (Grant No. 0305044201), and the Discipline Construction of Anhui Medical University (Grant No. 0301001836).