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Lycopene inhibits doxorubicin-induced heart failure by inhibiting ferroptosis through the Nrf2 signaling pathway

Rong Huang, Chao Zhou, Tianxiang Wang, Yuanli Chen, Zhouling Xie, Lingling Wei, Yajun Duan, Chenzhong Liao, Chuanrui Ma, Xiaoxiao Yang

2025Life Sciences14 citationsDOI

Topics & Concepts

DoxorubicinLycopeneSignal transductionChemistryHeart failurePharmacologyCell biologyCancer researchMedicineBiochemistryBiologyCarotenoidInternal medicineChemotherapyFerroptosis and cancer prognosisChemotherapy-induced cardiotoxicity and mitigationInflammatory Biomarkers in Disease Prognosis
Lycopene inhibits doxorubicin-induced heart failure by inhibiting ferroptosis through the Nrf2 signaling pathway | Litcius