Litcius/Paper detail

Bacterial infection reinforces host metabolic flux from arginine to spermine for NLRP3 inflammasome evasion

Jiatiao Jiang, Wenwen Wang, Fei Sun, Yuanxing Zhang, Qin Liu, Dahai Yang

2021Cell Reports26 citationsDOIOpen Access PDF

Abstract

efflux-dependent NLRP3 inflammasome activation. These data highlight the mechanism of bacterial gene-mediated arginine metabolism control for NLRP3 inflammasome evasion.

Topics & Concepts

InflammasomeSpermineEvasion (ethics)Flux (metallurgy)ArginineHost (biology)MicrobiologyArginaseBiologyCell biologyImmunologyChemistryInflammationImmune systemBiochemistryGeneticsEnzymeAmino acidOrganic chemistryInflammasome and immune disordersTryptophan and brain disordersNeonatal Health and Biochemistry