Mechanism of SOX10 in ferroptosis of hippocampal neurons after intracerebral hemorrhage via the miR-29a-3p/ACSL4 axis
Hui Chen, Lejia Ren, Wenbin Ma
Abstract
SOX10 promotes the expression of Mir-29a-3p by binding to the promoter region of Mir-29a-3p, thereby targeting the expression of ACSL4 and inhibiting the iron death of hippocampal neuronal cells in mice with ICH.
Topics & Concepts
Hippocampal formationNeuroscienceMechanism (biology)Intracerebral hemorrhageSOX10ChemistryBiologyMedicineAnesthesiaPhysicsBiochemistryNeural crestSubarachnoid hemorrhageQuantum mechanicsGeneFerroptosis and cancer prognosisCancer-related molecular mechanisms researchMicroRNA in disease regulation