Syntheses and Transformations of Sulfoximines
Wenting Zheng, Xianlie Chen, Feng Chen, Ze He, Qingle Zeng
Abstract
Sulfoximines are widely used as medicines, agricultural chemicals, chiral precursors, and chiral ligands in asymmetric synthesis, as well as pivotal intermediates for the construction of heterocyclic compounds. NH-sulfoximines may be synthesized from thioethers, sulfoxides, sulfilimines, and sulfinamides. NH-sulfoximines can undergo various transformations, such as arylations, alkylations, vinylations, and alkynylations. Here, we review the methods that have been applied to the syntheses and transformations of NH-sulfoximines.
Topics & Concepts
ChemistryCombinatorial chemistryOrganic chemistrySynthesis and Catalytic ReactionsSulfur-Based Synthesis TechniquesCatalytic C–H Functionalization Methods