Litcius/Paper detail

The proximity-enabled sulfur fluoride exchange reaction in the protein context

Bingchen Yu, Li Cao, Shanshan Li, Paul C. Klauser, Lei Wang

2023Chemical Science29 citationsDOIOpen Access PDF

Abstract

usage. These results advanced our understanding of SuFEx reactivity and kinetics in proteins, which is invaluable for ongoing exploration of SuFEx-enabled covalent proteins for basic biological research and creative biotherapeutics.

Topics & Concepts

FluorideContext (archaeology)SulfurChemistryInorganic chemistryOrganic chemistryGeographyArchaeologyMonoclonal and Polyclonal Antibodies ResearchClick Chemistry and ApplicationsVirus-based gene therapy research