An easy-to-use antimicrobial hydrogel effectively kills bacteria, fungi, and influenza virus
Brinta Bhattacharjee, Logia Jolly, Riya Mukherjee, Jayanta Haldar
Abstract
cells were reduced (3-4 log) in polymicrobial biofilms after hydrogel treatment. The hydrogel exhibited 99.9 % reduction of influenza viruses in a rapid manner. Due to the biocompatibility of Bacfuvir gel on topical application in a murine model and easy administration owing to its shear-thinning behaviour, this hydrogel can markedly contribute to mitigating drug-resistant bacterial, fungal and viral infections in healthcare settings.
Topics & Concepts
MicrobiologyAntimicrobialBacteriaCandida albicansBiofilmChemistryPathogenic bacteriaAntibacterial activityAntibioticsCorpus albicansBiologyGeneticsAntimicrobial agents and applicationsRespiratory viral infections researchAntimicrobial Peptides and Activities