Litcius/Paper detail

A systematic review and meta-analysis recite the efficacy of Tacrolimus treatment in renal transplant patients in association with genetic variants of <i>CYP3A5</i> gene.

Priyal M. Chauhan, Rashmi Hemani, Nilay Solanki, Nitiraj Shete, Sishir Gang, Abhijit Konnur, Ratika Srivastava, Sachchida Nand Pandey

2023PubMed11 citationsOpen Access PDF

Abstract

genetic variant (rs776746) analysis is relevant in personalizing the Tacrolimus dose determination in renal transplant patients.

Topics & Concepts

TacrolimusCYP3A5Meta-analysisMedicineGenetic modelPharmacogeneticsInternal medicineGenotypePharmacologyTransplantationBiologyGeneGeneticsRenal Transplantation Outcomes and TreatmentsPharmacological Effects and Toxicity StudiesPharmacogenetics and Drug Metabolism